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The haemolytic uraemic syndrome--a family study.

作者信息

Farr M J, Roberts S, Morley A R, Dewar D F, Uldall P R

出版信息

Q J Med. 1975 Apr;44(174):161-88.

PMID:1178809
Abstract

This study included patients, all relatives with the haemolytic uraemic syndrome, and 18 family members. The diagnosis was uncertain in one other and definite in four patients. Three of these four comprised a father and two of his children. Data are presented to emphasize the widespread nature of the disease. Other than hypertension, predisposing factors, and red cell and HL-A genetic markers, although sought, have not been found. Management is discussed with special reference to the one surviving patient. Early bilateral nephrectomy may be life-saving.

摘要

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Atypical haemolytic uraemic syndrome associated with a hybrid complement gene.与杂合补体基因相关的非典型溶血尿毒综合征
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Complement factor H gene mutation associated with autosomal recessive atypical hemolytic uremic syndrome.
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Acute glomerulonephritis and hemolytic uremic syndrome.
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