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微创食管肌层切开术后的结果

Outcomes after minimally invasive esophagomyotomy.

作者信息

Luketich J D, Fernando H C, Christie N A, Buenaventura P O, Keenan R J, Ikramuddin S, Schauer P R

机构信息

University of Pittsburgh Medical Center Health System, Pennsylvania, USA.

出版信息

Ann Thorac Surg. 2001 Dec;72(6):1909-12; discussion 1912-3. doi: 10.1016/s0003-4975(01)03127-7.

Abstract

BACKGROUND

Thoracic surgeons traditionally performed thoracotomy and myotomy for achalasia. Recently minimally invasive approaches have been reported with good success. This report summarizes our single-institution experience using video-assisted thoracoscopy (VATS) or laparoscopy (LAP) for the treatment of achalasia.

METHODS

A review of 62 patients undergoing minimally invasive myotomy for achalasia was performed. There were 27 male and 35 female patients. Mean age was 53 years (range 14 to 86). Thirty-seven (59.7%) had failed prior treatments (balloon dilation, botulinim toxin injection, or prior surgery). Outcomes studied were dysphagia score (1 = none, 5 = severe), Short-Form 36 quality of life (SF36 QOL) score, and heartburn-related QOL index (HRQOL).

RESULTS

Surgery included myotomy and partial fundoplication (5 VATS and 57 LAP). Mortality was zero, and complications occurred in 9 (14.5%) patients. There were 6 perforations (4 repaired by LAP and 2 open). Median length of stay was 2 days, time to oral intake was 1 day. At a mean of 19 months follow-up, 92.5% of patients were satisfied with outcome. Dysphagia scores improved from 3.6 to 1.5 (p < 0.01) but 3 patients ultimately required esophagectomy for recurrent dysphagia. HRQOL scores for heartburn and SF-36 QOL scores were comparable with control populations.

CONCLUSIONS

Minimally invasive myotomy and partial fundoplication for achalasia improved dysphagia in 92.5% of patients with heartburn and QOL scores were comparable with normal values at 19-month follow-up. The laparoscopic approach offers excellent results and was the preferred approach by our thoracic group for treating achalasia. Thoracic residency training should strive to include laparoscopic esophageal experience.

摘要

背景

传统上,胸外科医生采用开胸手术和肌切开术治疗贲门失弛缓症。最近有报道称,微创方法取得了良好的效果。本报告总结了我们单机构使用电视辅助胸腔镜(VATS)或腹腔镜(LAP)治疗贲门失弛缓症的经验。

方法

对62例行贲门失弛缓症微创肌切开术的患者进行回顾性研究。其中男性27例,女性35例。平均年龄53岁(范围14至86岁)。37例(59.7%)患者先前治疗(球囊扩张、肉毒杆菌毒素注射或先前手术)失败。研究的结果指标包括吞咽困难评分(1 = 无,5 = 严重)、简明健康状况调查量表36项生活质量(SF36 QOL)评分以及烧心相关生活质量指数(HRQOL)。

结果

手术包括肌切开术和部分胃底折叠术(5例VATS和57例LAP)。死亡率为零,9例(14.5%)患者出现并发症。有6例穿孔(4例通过LAP修复,2例开腹修复)。中位住院时间为2天,开始经口进食时间为1天。平均随访19个月时,92.5%的患者对治疗结果满意。吞咽困难评分从3.6改善至1.5(p < 0.01),但3例患者最终因复发性吞咽困难需要行食管切除术。烧心的HRQOL评分和SF - 36 QOL评分与对照组人群相当。

结论

贲门失弛缓症的微创肌切开术和部分胃底折叠术使92.5%有烧心症状的患者吞咽困难得到改善,且在19个月随访时生活质量评分与正常值相当。腹腔镜手术效果极佳,是我们胸外科团队治疗贲门失弛缓症的首选方法。胸外科住院医师培训应努力纳入腹腔镜食管手术经验。

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