Barr R D, Whang-Peng J, Perry S
Science. 1975 Oct 17;190(4211):284-5. doi: 10.1126/science.1179209.
A population of lymphocytes, separable from the great majority by virtue of their larger size and their failure to exhibit the rosetting characteristics of thymus-dependent lymphocytes and bursa-equivalent cells, possess true pluripotentiality. On culture in vivo they proliferate and differentiate into erythrocytic, granulocytic, and megakaryocytic progeny. This may be the first clear demonstration of the primitive progenitor blood cell in man.
一群淋巴细胞，因其较大的体积以及不具备胸腺依赖性淋巴细胞和法氏囊等效细胞的玫瑰花结形成特征，可与绝大多数细胞分离，它们具有真正的多能性。在体内培养时，它们会增殖并分化为红细胞、粒细胞和巨核细胞后代。这可能是人类原始祖血细胞的首个明确例证。
