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子宫内膜癌的预后因素。

Prognostic factors in endometrial carcinoma.

作者信息

De Mûelenaere G F

出版信息

S Afr Med J. 1975 Sep 27;49(41):1695-8.

PMID:1179240
Abstract

An analysis of 78 patients with surgical stage 1 adenocarcinoma of the endometrium reveals that several factors influence the prognosis. Differentiation of the tumour, and the depth of the uterine cavity, play a role, but a depth of 10 cm seems to be of greater assistance in prognostication than one of 8 cm. The menopausal state is very important, since not one patient who was less than 5 years postmenopausal died from carcinoma, and the majority who developed metastases were between 5 and 10 years postmenopausal. Prognosis did seem to be dependent on age, since the group aged between 60 and 70 years had the worst prognosis. Crude survival figures are useless for determining prognostic factors, and an analysis of patients dying from carcinoma must be made. That definite factors besides the method of treatment affect the survival of patients, makes it virtually impossible to make an accurate comparison of survival figures in different series.

摘要

对78例手术分期为1期的子宫内膜腺癌患者的分析显示,有几个因素会影响预后。肿瘤的分化程度以及子宫腔深度都有影响,不过10厘米的深度似乎比8厘米的深度在预后判断上更有帮助。绝经状态非常重要,因为绝经后不到5年的患者无一死于癌症,而发生转移的大多数患者处于绝经后5至10年。预后似乎确实取决于年龄,因为60至70岁的患者组预后最差。粗略的生存数据对于确定预后因素毫无用处,必须对死于癌症的患者进行分析。除了治疗方法之外,还有其他明确因素会影响患者的生存,这使得几乎不可能准确比较不同系列中的生存数据。

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