Giordana C, Malinverni G, Rosmino C, Del Tetto F, Ravarino N, Sala S
Divisione di Radioterapia, Ospedale Mauriziano Umberto, Torino.
Radiol Med. 1991 Mar;81(3):342-5.
We report the results of the combined use of surgery and radiation therapy in the treatment of endometrial carcinoma. From January 1974 to December 1989, 89 cases were treated by means of abdominal hysterectomy followed by external radiation therapy. Actuarial survival at 5 years is 100% for stage I, 75% for stage II, and 42.86% for stage III; stage IV patients could not be evaluated. Prognostic factors were statistically significant. In stages II and III survival rates were directly related to histological grading (G1: 90.91%; G2: 81.82%; G3: 25%) and to myometrial infiltration (M1: 85.71%; M2: 81.82%; M3: 70%). Generally, survival was related to age, and prognosis was better in younger patients (under 55) and depended on lymph nodal involvement (N-: 88.24%, versus N+: 25%). Vaginal and pelvic recurrences were 8 (10.1%), and deaths were 13. The identification of high-risk patients will make it possible to select an even more adequate treatment.
我们报告了手术与放射治疗联合用于子宫内膜癌治疗的结果。1974年1月至1989年12月期间，89例患者接受了经腹子宫切除术加体外放射治疗。I期患者5年精算生存率为100%，II期为75%，III期为42.86%；IV期患者无法评估。预后因素具有统计学意义。在II期和III期，生存率与组织学分级（G1：90.91%；G2：81.82%；G3：25%）以及肌层浸润（M1：85.71%；M2：81.82%；M3：70%）直接相关。一般来说，生存率与年龄有关，年轻患者（55岁以下）预后较好，且取决于淋巴结受累情况（N-：88.24%，而N+：25%）。阴道和盆腔复发8例（10.1%），死亡13例。识别高危患者将有助于选择更合适的治疗方法。
