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髋臼模块化对全髋关节置换术中聚乙烯磨损和骨溶解的影响。

Effect of acetabular modularity on polyethylene wear and osteolysis in total hip arthroplasty.

作者信息

Young Anthony M, Sychterz Christi J, Hopper Robert H, Engh Charles A

机构信息

Anderson Orthopaedic Research Institute, Alexandria, VA 22307, USA.

出版信息

J Bone Joint Surg Am. 2002 Jan;84(1):58-63. doi: 10.2106/00004623-200201000-00009.

Abstract

BACKGROUND

Debris from polyethylene wear causes osteolysis. In this study, we examined the effect of acetabular liner modularity on polyethylene wear and osteolysis.

METHODS

We compared forty-one hips (thirty-nine patients) treated with a nonmodular, porous-coated acetabular component with a matched group of forty-one hips (forty patients) treated with a modular acetabular component. The groups were matched by patient gender and age, type of polyethylene material, method of polyethylene sterilization, femoral head size and manufacturer, and stem manufacturer. The mean follow-up period was 5.3 years (range, 3.8 to 6.8 years) for the nonmodular group and 5.5 years (range, 3.8 to 8.0 years) for the modular group. Using serial radiographs and a computer-assisted method, we measured two-dimensional head penetration into the polyethylene liner. Temporal head-penetration data and linear regression analysis were used to calculate the true wear rates.

RESULTS

The nonmodular acetabular components demonstrated a lower, but not a significantly lower, mean true wear rate than did the modular components (0.11 compared with 0.16 mm/yr, p = 0.22), and they were associated with a significantly lower rate of osteolysis (2% compared with 22%, p = 0.01). In addition, the true wear rates of the nonmodular components were less variable than those of the modular components. The 95% confidence interval for the wear rates of the nonmodular components (0.08 to 0.13 mm/yr) was nearly half that of the modular group (0.11 to 0.20 mm/yr).

CONCLUSIONS

The lower and more consistent true wear rates of the nonmodular components could be attributed to the fact that these cups were designed to have greater liner-shell conformity, greater liner thickness, and less liner-shell micromotion than modular components. These design factors could have favorably altered the stress distribution throughout the liner and could have thereby decreased wear. Although nonmodular components may present a partial solution to the problems of wear and osteolysis, they pose a disadvantage when a failed liner in a bone-ingrown acetabular component needs to be revised.

摘要

背景

聚乙烯磨损产生的碎屑会导致骨溶解。在本研究中,我们研究了髋臼内衬模块化对聚乙烯磨损和骨溶解的影响。

方法

我们将41例使用非模块化、多孔涂层髋臼组件治疗的髋关节(39例患者)与一组匹配的41例使用模块化髋臼组件治疗的髋关节(40例患者)进行比较。两组在患者性别和年龄、聚乙烯材料类型、聚乙烯灭菌方法、股骨头尺寸和制造商以及股骨柄制造商方面进行匹配。非模块化组的平均随访期为5.3年(范围3.8至6.8年),模块化组为5.5年(范围3.8至8.0年)。使用系列X线片和计算机辅助方法,我们测量了股骨头在聚乙烯内衬中的二维穿透情况。利用时间相关的股骨头穿透数据和线性回归分析来计算实际磨损率。

结果

非模块化髋臼组件的平均实际磨损率低于模块化组件,但差异无统计学意义(分别为0.11与0.16mm/年,p = 0.22),且其骨溶解发生率显著较低(分别为2%与22%,p = 0.01)。此外,非模块化组件的实际磨损率变化比模块化组件小。非模块化组件磨损率的95%置信区间(0.08至0.13mm/年)几乎是模块化组(0.11至0.20mm/年)的一半。

结论

非模块化组件较低且更一致的实际磨损率可能归因于这些髋臼杯的设计使其内衬与外壳的贴合度更高、内衬厚度更大且内衬与外壳之间的微动更小。这些设计因素可能有利地改变了整个内衬的应力分布,从而减少了磨损。尽管非模块化组件可能为磨损和骨溶解问题提供部分解决方案,但当需要翻修骨长入型髋臼组件中的失效内衬时,它们存在劣势。

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