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一体式杯是否能提高非骨水泥全髋关节置换术的生存率、减少磨损或降低骨溶解?

Do monoblock cups improve survivorship, decrease wear, or reduce osteolysis in uncemented total hip arthroplasty?

机构信息

Clinical Orthopedic Research Center-midden Nederland (CORC-mN), Department of Orthopaedics, Diakonessenhuis Hospital, PO Box 80250, 3508 TG, Utrecht, The Netherlands,

出版信息

Clin Orthop Relat Res. 2013 Nov;471(11):3572-80. doi: 10.1007/s11999-013-3144-y. Epub 2013 Aug 3.

Abstract

BACKGROUND

Monoblock acetabular components used in uncemented total hip arthroplasty (THA) have certain mechanical characteristics that potentially reduce acetabular osteolysis and polyethylene wear. However, the degree to which they achieve this goal is not well documented.

QUESTIONS/PURPOSES: The purpose of this study was to use a systematic review of controlled trials to test the hypothesis that monoblock cups have superior (1) polyethylene wear rate; (2) frequency of cup migration; (3) frequency of acetabular osteolysis; and (4) frequency of aseptic loosening compared with modular components used in uncemented THA.

METHODS

A systematic search was conducted in the Medline, Embase, and Cochrane electronic databases to assemble all controlled trials comparing monoblock with modular uncemented acetabular components in primary THA. Included studies were considered "best evidence" if the quality score was either ≥ 50% on the Cochrane Back Review Group checklist or ≥ 75% the Newcastle-Ottawa quality assessment scale. A total of seven publications met our inclusion criteria.

RESULTS

Best evidence analysis showed no difference in polyethylene wear rate, the frequency of cup migration, and aseptic loosening between monoblock and modular acetabular components. No convincing evidence was found for the claim that lower frequencies of acetabular osteolysis are observed with the use of monoblock cups compared with modular uncemented cups.

CONCLUSIONS

The purported benefits of monoblock cups were not substantiated by this systematic review of controlled studies in that polyethylene wear rates and frequencies of cup failure and acetabular osteolysis were similar to those observed with modular implants. Other factors should therefore drive implant selection in cementless THA.

摘要

背景

在非骨水泥全髋关节置换术 (THA) 中使用整体式髋臼组件具有一定的机械特性,可潜在减少髋臼骨溶解和聚乙烯磨损。然而,它们实现这一目标的程度并没有得到很好的记录。

问题/目的:本研究旨在通过对对照试验的系统回顾来检验以下假设:与非骨水泥 THA 中使用的模块化组件相比,整体式杯具有以下优势:(1) 更高的聚乙烯磨损率;(2) 更高的杯迁移频率;(3) 更高的髋臼骨溶解频率;(4) 更高的无菌性松动频率。

方法

在 Medline、Embase 和 Cochrane 电子数据库中进行了系统搜索,以汇集所有比较整体式与模块化非骨水泥髋臼组件在初次 THA 中的对照试验。如果质量评分在 Cochrane 回顾小组检查表上≥50%或在纽卡斯尔-渥太华质量评估量表上≥75%,则认为这些研究为“最佳证据”。共有七篇文献符合我们的纳入标准。

结果

最佳证据分析显示,整体式和模块化髋臼组件在聚乙烯磨损率、杯迁移频率和无菌性松动方面无差异。没有令人信服的证据表明,与使用模块化非骨水泥杯相比,整体式杯可降低髋臼骨溶解的频率。

结论

本系统综述的对照研究并未证实整体式杯的所谓益处,因为聚乙烯磨损率以及杯失败和髋臼骨溶解的频率与模块化植入物相似。因此,在非骨水泥 THA 中,应选择其他因素来驱动植入物的选择。

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