急性脱髓鞘性脑脊髓炎（ADEM）患者的扩散加权磁共振成像和灌注加权磁共振成像

Diffusion- and perfusion-weighted MR imaging in a patient with acute demyelinating encephalomyelitis (ADEM).

作者信息

Bernarding Johannes, Braun Jürgen, Koennecke Hans-Christian

机构信息

Department of Medical Informatics, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin, Berlin, Germany.

出版信息

J Magn Reson Imaging. 2002 Jan;15(1):96-100. doi: 10.1002/jmri.10045.

DOI:10.1002/jmri.10045

PMID:11793463

Abstract

To monitor changes of brain tissue metabolism in acute demyelinating encephalitis (ADEM), we examined a patient with suspected ADEM by serial MRI including diffusion- and perfusion-weighted imaging (DWI, PWI). Within the inflammatory tissue, the apparent diffusion coefficients were reduced, normal, and increased. Perfusion varied between reduced and normal values, except for small hyperperfused regions. Combining standard MRI with DWI and PWI may elucidate different overlapping phases in cerebral inflammation.

摘要

为监测急性脱髓鞘性脑炎（ADEM）脑组织代谢的变化，我们通过包括弥散加权成像（DWI）和灌注加权成像（PWI）在内的系列磁共振成像（MRI）检查了一名疑似ADEM的患者。在炎性组织内，表观扩散系数降低、正常及升高。灌注在降低和正常数值之间变化，除了小的高灌注区域。将标准MRI与DWI和PWI相结合可能有助于阐明脑内炎症不同的重叠阶段。