Suciu D, Uray Z, Abraham A D
Strahlentherapie. 1975 Aug;150(2):149-53.
Mice were whole-body irradiated with 300, 500 and 800 rd (60Co) one hour or three days after administration of 3H-thymidine. The time courses of the total and specific activity of DNA indicate that three days after exposure with 500 and 800 rd the mitotically active cells were selectively lost from the small intestine. The release of labelled DNA was determined in the fraction of DNA soluble in 0.14 N NaCl. The results suggest that the relatively small fraction of soluble DNA belongs to the mitotically active cells probably having died in the interphase.
在给予3H-胸腺嘧啶核苷1小时或3天后，用300、500和800拉德（60Co）对小鼠进行全身照射。DNA总活性和比活性的时间进程表明，在接受500和800拉德照射3天后，有丝分裂活跃细胞从小肠中被选择性地清除。通过测定可溶于0.14N氯化钠的DNA部分中标记DNA的释放量。结果表明，可溶性DNA相对较小的部分可能属于在间期死亡的有丝分裂活跃细胞。
