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[皮肤放射治疗中特征性自动射线的利用可能性]

[Exploitation possibilities of characteristic autoradiations for dermatological radiotherapy].

作者信息

Schirren J M

出版信息

Strahlentherapie. 1975 Aug;150(2):162-83.

PMID:1179447
Abstract

Several reasons, especially radioprotection of non-affected strata, seem to make it necessary to look for X-ray qualities which effect - in the diseased dermal layers - a more appropriate dose distribution than it was possible to achieve by the X-ray units used so far. Therefore, the possibilities to utilize characteristic autoradiations are examined, i.e. those possibilities being at disposal in the soft-ray range. Practically, there are the series "K" of copper and molybdenum - maybe also those of silver - coming into the question. Using X-ray tubes with copper and molybdenum anodes, the following items are determined, under D.C. operation, in comparison to the wolfram anode tubes which were usually operated until now: Parts of the characteristic autoradiation in the mixture of rays, half-value thicknesses, relative depth doses, stratified half-value depths, the "rates of tissue homogeneity", and - with regard to special care for deeper strate - the "one-tenth value depths" as well as "depth stress factors". The determinations were effected right in dependence on tube tension and focus - skin - distance. The results of the studies, partly demonstrated by practical examples, show that an X-radiation within the so-called soft-ray range corresponds so much the more to the up-to-date conceptions of radioprotection, as this radiation is accepting the characteristics of the monochromatic autoradiation of the anode material. From the clinical point of view, it remains to be exmained preferably whether there will ever be an indication in the range of dermatological radiotherapy that needs a harder quality of rays than those of the molybdene series K.

摘要

有几个原因,尤其是对未受影响层的辐射防护,似乎使得有必要寻找这样的X射线特性:在患病的真皮层中,它能产生比迄今使用的X射线装置所能实现的更合适的剂量分布。因此,研究了利用特征性自动辐射的可能性,即在软射线范围内可用的那些可能性。实际上,铜和钼的“K”系列——也许还有银的——都值得考虑。与目前通常使用的钨靶X射线管相比,使用铜靶和钼靶X射线管,在直流运行条件下测定以下各项:射线混合物中特征性自动辐射的部分、半价层厚度、相对深度剂量、分层半价深度、“组织均匀率”,以及——对于对更深层的特别关注——“十分之一值深度”以及“深度应力因子”。这些测定是直接根据管电压和焦点 - 皮肤距离进行的。部分通过实际例子展示的研究结果表明,所谓软射线范围内的X辐射越符合最新的辐射防护概念,因为这种辐射具有阳极材料单色自动辐射的特性。从临床角度来看,最好仍有待研究在皮肤科放射治疗范围内是否会有任何需要比钼系列K射线更硬的射线质量的指征。

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