Marck K W, Spijkervet F K
Afdeling Mondziekten, Kaakchirurgie en Bijzondere Tandheelkunde, Academisch Ziekenhuis Groningen.
Ned Tijdschr Tandheelkd. 2001 Dec;108(12):496-9.
Noma (cancrum oris, water cancer) is an orofacial gangrene that may develop in malnutritioned children debilitated by concomitant diseases as measles. It has been hypothesized that the gangrene originates from acute necrotizing gingivitis, common in malnourished children in developing countries. In previous centuries noma was common in the Western world. The affection disappeared when economical progress permitted the poorest to feed their children sufficiently. The yearly incidence of noma in the world is estimated as 140,000. The mortality is +/- 90%. The facial deformities of those who survive noma are generally serious. Beside facial mutilations, oral functions are hampered (trismus, oral incontinence, impaired speech). Both prevention (improved feeding, measles vaccination) as the treatment of those who contract and survive noma are a challenge for the 'global village' of the modern world.
走马疳(口颊坏疽、水癌)是一种口面部坏疽,可能发生于因麻疹等伴发疾病而虚弱的营养不良儿童。据推测,这种坏疽起源于急性坏死性龈炎,在发展中国家营养不良的儿童中很常见。在过去几个世纪里,走马疳在西方世界很常见。当经济发展使最贫困的人能够充分养活孩子时,这种疾病就消失了。据估计,全世界走马疳的年发病率为14万。死亡率约为90%。走马疳幸存者的面部畸形通常很严重。除了面部毁容外,口腔功能也受到阻碍(牙关紧闭、口腔失禁、言语障碍)。预防(改善喂养、麻疹疫苗接种)以及对感染走马疳并存活下来的患者的治疗,都是现代世界“地球村”面临的挑战。