Reagent-controlled stereoselective iodolactonizations.
作者信息
Haas Jürgen, Piguel Sandrine, Wirth Thomas
机构信息
Department of Chemistry, Cardiff University, P.O. Box 912, Cardiff CF10 3TB, UK.
出版信息
Org Lett. 2002 Jan 24;4(2):297-300. doi: 10.1021/ol0171113.
PMID:11796074
Abstract
[reaction: see text] Iodocyclizations are important transformations and among stereocontrolled iodocyclizations mostly substrate-controlled versions using a chiral auxiliary have been successfully investigated. This work reports on stereoselective reagent-controlled iodolactonizations applying a new method using a combination of ICl and a primary amine leading to the highest selectivities known so far.
摘要
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