Haagsma J
Zentralbl Bakteriol Orig A. 1975 Jan;230(1):59-66.
This study has shown for the first time that fish such as eels (Anguilla anguilla L.) and carp (Cyprinus carpio L.) are sensitive to type E botulinum toxin. With oral administration the MLD for eels was 27.500 mouse LD50 per kg body weight, while for carp it was only 236 mouse LD50 per kg. Carp were also found to be sensitive to a slight degree to type C botulinum toxin, the MLD of the most virulent toxin of this type being 457,000 mouse LD50 per kg with oral administration. Eels, however, showed no sensitivity to type C toxin.
本研究首次表明,鳗鱼(Anguilla anguilla L.)和鲤鱼(Cyprinus carpio L.)等鱼类对E型肉毒杆菌毒素敏感。经口服给药,鳗鱼的半数致死量(MLD)为每千克体重27,500个小鼠半数致死量(LD50),而鲤鱼仅为每千克236个小鼠LD50。还发现鲤鱼对C型肉毒杆菌毒素有轻微敏感性,经口服给药,该型最具毒性的毒素的MLD为每千克457,000个小鼠LD50。然而,鳗鱼对C型毒素不敏感。