Alanko K, Kahanpää A, Pätiälä J
Acta Med Scand. 1975 Sep;198(3):235-40. doi: 10.1111/j.0954-6820.1975.tb19533.x.
Endemic areas of coccidioidomycosis are described. The mycology of Coccidioides immitis is reviewed, with special reference to the risk of laboratory infection. A classification of coccidioidomycosis is listed and two cases from Finland are presented. The first patient had typical X-ray and clinical findings, including a positive coccidioidin test. The second case, occurring soon after a visit to Arizona, was confirmed by positive fungal cultures from the sputum and from a resected specimen. Because the latter patient became pregnant and the risk of dissemination was considered great, legal abortion was performed. The resection of the pulmonary cavitation with infiltration around it took place under coverage of pre- and postoperative amphotericin B medication. Complete recovery was obtained. The indications for thoracic surgery are briefly listed. Diagnostic and mycologic aspects of this rare and exotic disease are discussed. Among other things, the importance of a good medical history in finding the contact with infective environment or material is stressed.
描述了球孢子菌病的流行地区。回顾了粗球孢子菌的真菌学,特别提及实验室感染的风险。列出了球孢子菌病的分类,并介绍了来自芬兰的两例病例。第一例患者有典型的X线和临床症状,包括球孢子菌素试验阳性。第二例病例在访问亚利桑那州后不久发生,痰液和切除标本的真菌培养呈阳性得以确诊。由于后一名患者怀孕且认为播散风险很大,遂进行了合法堕胎。在术前和术后使用两性霉素B药物的情况下,对肺部空洞及其周围浸润进行了切除。患者完全康复。简要列出了胸外科手术的指征。讨论了这种罕见的外来疾病的诊断和真菌学方面。其中强调了详细病史对于发现与感染环境或物质接触的重要性。