Moreno C, Jacyk W K, Judd M J, Requena L
Department of Pathology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.
Am J Dermatopathol. 2001 Oct;23(5):450-5. doi: 10.1097/00000372-200110000-00011.
Extraocular sebaceous carcinoma is an uncommon neoplasm usually localized on the head and neck. We report a case of sebaceous carcinoma of the axillary skin with a highly aggressive behavior. The patient was a 43-year-old black man who developed multiple cutaneous and lymph node metastases shortly after the excision of primary sebaceous carcinoma of the axillary skin. Many neoplastic aggregations were identified within the lumina of the dermal lymphatic vessels in the excised specimen of the primary neoplasm. Although extraocular sebaceous carcinoma has been traditionally considered a less aggressive neoplasm than its ocular counterpart, a review of the literature and this case demonstrate that extraocular sebaceous carcinoma may also lead to disseminated metastatic disease.
眼外皮脂腺癌是一种罕见的肿瘤，通常位于头颈部。我们报告一例具有高度侵袭性的腋窝皮肤皮脂腺癌病例。患者为一名43岁黑人男性，在切除腋窝皮肤原发性皮脂腺癌后不久即出现多处皮肤和淋巴结转移。在原发性肿瘤切除标本的真皮淋巴管腔内发现了许多肿瘤细胞团。尽管传统上认为眼外皮脂腺癌的侵袭性低于眼内皮脂腺癌，但文献回顾及本病例表明，眼外皮脂腺癌也可能导致播散性转移性疾病。
