Verse Thomas, Maurer Joachim T, Pirsig Wolfgang
Department of Otorhinolaryngology, Head and Neck Surgery, Section for Rhinology and Rhonchopathies, University of Ulm, Ulm, Germany.
Laryngoscope. 2002 Jan;112(1):64-8. doi: 10.1097/00005537-200201000-00012.
OBJECTIVE/HYPOTHESIS: Single cases of patients who have experienced obstructive sleep apnea (OSA) and who recovered completely after nasal surgery have been described in various studies. The purpose of this study was to evaluate the efficacy of only nasal surgery 1) in a group of patients with obstructive sleep apnea and 2) in simple snorers.
A prospective, controlled study with 26 adult patients who underwent nasal surgery as single treatment of their sleep-related breathing disorders. The cases were evaluated based on the severity level of their preoperative Apnea Hypopnea Index (AHI).
Between August 1996 and July 2000, 26 patients who snored and had impaired nasal breathing underwent attended polysomnography in the sleep laboratory as single treatment nasal surgery was performed. Postoperative polysomnographic findings and complications were reviewed.
Nineteen of 26 patients (73.1%) were diagnosed as having OSA. Seven patients were simple snorers with an AHI below 10. The surgical response rates, defined as greater than or equal to 50% reduction in the postoperative AHI and a postoperative AHI of less than 20, was 15.8% in the apneics. For the whole group, the AHI decreased postoperatively from 31.6 to 28.9. However, daytime sleepiness improved significantly and arousals decreased significantly in both apneics and simple snorers after nasal surgery.
We conclude that nasal surgery has a limited efficacy in the treatment of adult patients with sleep apnea. Nevertheless, nasal surgery significantly improves sleep quality and daytime sleepiness independent of the severity of obstructive sleep-related breathing disorders.
目的/假设:多项研究描述了阻塞性睡眠呼吸暂停(OSA)患者经鼻腔手术后完全康复的个别病例。本研究的目的是评估单纯鼻腔手术对以下两类患者的疗效:1)一组阻塞性睡眠呼吸暂停患者;2)单纯打鼾者。
一项前瞻性对照研究,纳入26例接受鼻腔手术作为睡眠相关呼吸障碍单一治疗方法的成年患者。根据术前呼吸暂停低通气指数(AHI)的严重程度对病例进行评估。
1996年8月至2000年7月,26例打鼾且存在鼻呼吸障碍的患者在睡眠实验室接受了多导睡眠监测,随后进行了单纯鼻腔手术。对术后多导睡眠监测结果和并发症进行了回顾。
26例患者中有19例(73.1%)被诊断为患有阻塞性睡眠呼吸暂停。7例为单纯打鼾者,AHI低于10。手术缓解率定义为术后AHI降低大于或等于50%且术后AHI小于20,在呼吸暂停患者中为15.8%。对于整个组,术后AHI从31.6降至28.9。然而,鼻腔手术后,呼吸暂停患者和单纯打鼾者的日间嗜睡情况均显著改善,觉醒次数显著减少。
我们得出结论,鼻腔手术在治疗成年睡眠呼吸暂停患者方面疗效有限。尽管如此,鼻腔手术能显著改善睡眠质量和日间嗜睡情况,且与阻塞性睡眠相关呼吸障碍的严重程度无关。