Referowska M
Anaesth Resusc Intensive Ther. 1975 Apr-Jun;3(2):141-6.
The results of determinations of some factors of the blood clotting and fibrinolysis systems carried out in 30 patients operated on under anaesthesia with neuroleptanalygesics are reported. The factors determined included: the time of spontaneous lysis of whole blood clot, the euglobulin lysis time, the fibrinolytic activity on Astrup plates, the fibrinogen level and platelet count. The purpose of this work was to demonstrate a possible action of neuroleptanagetic agents on the system maintaining the blood in equilibrium. The fibrinolytic activity was not increased but the fibrinogen level and platelet count were decreased. These changes, however, seem to depend on the effects of the surgical operation and not on the method of anaesthesia used.
报告了对30例在神经安定镇痛麻醉下接受手术的患者进行的一些凝血和纤维蛋白溶解系统因素测定的结果。所测定的因素包括：全血凝块自发溶解时间、优球蛋白溶解时间、阿斯特鲁普平板上的纤维蛋白溶解活性、纤维蛋白原水平和血小板计数。这项工作的目的是证明神经安定镇痛剂对维持血液平衡系统可能产生的作用。纤维蛋白溶解活性没有增加，但纤维蛋白原水平和血小板计数降低。然而，这些变化似乎取决于手术操作的影响，而不是所用的麻醉方法。
