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用于假体稳定的骨水泥对血液凝固系统活性的影响。

The effect of bone cement used for stabilization of endoprostheses on blood clotting system activity.

作者信息

Gaszyński W, Lewicki R, Pruszyńska-Bednarek A

出版信息

Anaesth Resusc Intensive Ther. 1976 Oct-Dec;4(4):237-44.

PMID:1024473
Abstract

The authors carried out studies of the blood clotting and fibrinolysis systems in 15 patients undergoing total endoprosthetic replacement of the hip joint with a McKee-Ferrara type of prosthesis and stabilized by Surgical Simplex Acrylic bone cement (North Hill Plastics, Ltd. London). The observations point to statistically significant changes in the blood clotting and fibrinolysis systems with a tendency towards hypercoagulation and intravascular clotting (DIC). Fibrinolysis activation associated with these changes is secondary, resulting among others, from the mechanism of the action of free fibrin monomers.

摘要

作者对15例接受McKee-Ferrara型假体全髋关节置换术并用Surgical Simplex丙烯酸骨水泥(伦敦北山塑料有限公司)固定的患者的凝血和纤维蛋白溶解系统进行了研究。观察结果表明,凝血和纤维蛋白溶解系统发生了具有统计学意义的变化,有高凝和血管内凝血(弥散性血管内凝血)的倾向。与这些变化相关的纤维蛋白溶解激活是继发性的,部分是由游离纤维蛋白单体的作用机制导致的。

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