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Silymarin, an inhibitor of lipoxygenase.

作者信息

Fiebrich F, Koch H

出版信息

Experientia. 1979 Dec 15;35(12):1548-60. doi: 10.1007/BF01953184.

DOI:10.1007/BF01953184
PMID:118048
Abstract

Silybin (I), silydianin (II) and silychristin (III), the constituents of silymarin, non-competitively inhibit the lipoxygenase from soybeans (EC 1.13.11.12) in vitro.

摘要

相似文献

1
Silymarin, an inhibitor of lipoxygenase.
Experientia. 1979 Dec 15;35(12):1548-60. doi: 10.1007/BF01953184.
2
Silymarin, an inhibitor of prostaglandin synthetase.
Experientia. 1979 Dec 15;35(12):1550-2. doi: 10.1007/BF01953185.
3
[Silymarin--an inhibitor of horseradish peroxidase (author's transl)].
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Silymarin: potent inhibitor of cyclic AMP phosphodiesterase.水飞蓟素：环磷酸腺苷磷酸二酯酶的强效抑制剂。
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Activities of silymarin and its flavonolignans upon low density lipoprotein oxidizability in vitro.水飞蓟素及其黄酮木脂素对低密度脂蛋白体外氧化能力的影响。
Phytother Res. 1999 Sep;13(6):535-7. doi: 10.1002/(sici)1099-1573(199909)13:6<535::aid-ptr526>3.0.co;2-w.
6
[Peroxidase isoenzymes in cress seedlings (Lepidium sativum L.) and their inhibition by silybin, silydianin and silychristin].
Experientia. 1977 Dec 15;33(12):1568-9. doi: 10.1007/BF01934001.
7
Advances in pharmacological studies of silymarin.
Mem Inst Oswaldo Cruz. 1991;86 Suppl 2:79-85. doi: 10.1590/s0074-02761991000600020.
8
Anti-inflammatory and anti-arthritic activities of silymarin acting through inhibition of 5-lipoxygenase.水飞蓟素通过抑制5-脂氧合酶发挥抗炎和抗关节炎活性。
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Role of Silymarin in Cancer Treatment: Facts, Hypotheses, and Questions.水飞蓟素在癌症治疗中的作用：事实、假设和问题。
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A review on the mechanisms of the effect of silymarin in milk thistle (Silybum marianum) on some laboratory animals.

本文引用的文献

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Spectrophotometric Method for Determination of Lipoxidase Activity.分光光度法测定脂氧化酶活性
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The determination of enzyme inhibitor constants.酶抑制剂常数的测定
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On the specificity of the lipoxidase catalyzed oxygenation of unsaturated fatty acids.
Biochem Biophys Res Commun. 1965 Dec 21;21(6):531-6. doi: 10.1016/0006-291x(65)90517-6.
水飞蓟宾（奶蓟草）中水飞蓟素对一些实验动物作用机制的综述。
Vet Med Sci. 2022 Jan;8(1):289-301. doi: 10.1002/vms3.641. Epub 2021 Oct 2.
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Treatment of Osteoarthritis With Low-level Laser Therapy, Acupuncture, and Herbal Therapy: A Case Report.低强度激光疗法、针灸和草药疗法治疗骨关节炎：一例报告
Integr Med (Encinitas). 2018 Apr;17(2):48-53.
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Seed germination and biochemical profile of exposed to monometallic and bimetallic alloy nanoparticles.暴露于单金属和双金属合金纳米颗粒的种子萌发及生化特征
IET Nanobiotechnol. 2016 Dec;10(6):359-366. doi: 10.1049/iet-nbt.2015.0050.
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The flavonoids: a brief review and study of effects on antigen-induced histamine release from human basophils.黄酮类化合物：对抗原诱导人嗜碱性粒细胞释放组胺作用的简要综述与研究
Trans Am Clin Climatol Assoc. 1981;92:234-52.
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Silymarin, an inhibitor of prostaglandin synthetase.
Experientia. 1979 Dec 15;35(12):1550-2. doi: 10.1007/BF01953185.
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[On the pharmacology and toxicology of silymarin, an antihepatotoxic active principle from Silybum marianum (L.) Gaertn].
Arzneimittelforschung. 1968 Jun;18(6):698-704.
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A convenient method for lipoxygenase isoenzyme determination.
Anal Biochem. 1971 Dec;44(2):642-4. doi: 10.1016/0003-2697(71)90254-5.
6
[Silymarin prevents peroxidation of lipids in carbon tetrachloride-induced liver damage].水飞蓟素可预防四氯化碳诱导的肝损伤中的脂质过氧化。
Experientia. 1973 Nov 15;29(11):1372. doi: 10.1007/BF01922826.
7
[The chemistry and analysis of silymarin from Silybum marianum Gaertn].[水飞蓟宾的化学性质及分析，水飞蓟宾来自水飞蓟（Silybum marianum Gaertn）]
Arzneimittelforschung. 1974 Apr;24(4):466-71.
8
Iron, an essential component of lipoxygenase.铁，脂氧合酶的一种必需成分。
J Biol Chem. 1974 May 25;249(10):3183-6.
9
Chemicals, drugs, and lipid peroxidation.化学物质、药物与脂质过氧化作用。
Annu Rev Pharmacol Toxicol. 1976;16:125-41. doi: 10.1146/annurev.pa.16.040176.001013.
10
Silymarin, an inhibitor of prostaglandin synthetase.
Experientia. 1979 Dec 15;35(12):1550-2. doi: 10.1007/BF01953185.