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Silymarin, an inhibitor of prostaglandin synthetase.

作者信息

Fiebrich F, Koch H

出版信息

Experientia. 1979 Dec 15;35(12):1550-2. doi: 10.1007/BF01953185.

DOI:10.1007/BF01953185
PMID:118049
Abstract

Silybin (I), silydianin (II) and silychristin (III), the main constituents of silymarin, inhibit the formation of prostaglandins in vitro. The inhibition is log-linearly dependent on the concentration of the effectors.

摘要

相似文献

1
Silymarin, an inhibitor of prostaglandin synthetase.
Experientia. 1979 Dec 15;35(12):1550-2. doi: 10.1007/BF01953185.
2
Silymarin, an inhibitor of lipoxygenase.
Experientia. 1979 Dec 15;35(12):1548-60. doi: 10.1007/BF01953184.
3
Activities of silymarin and its flavonolignans upon low density lipoprotein oxidizability in vitro.水飞蓟素及其黄酮木脂素对低密度脂蛋白体外氧化能力的影响。
Phytother Res. 1999 Sep;13(6):535-7. doi: 10.1002/(sici)1099-1573(199909)13:6<535::aid-ptr526>3.0.co;2-w.
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Silymarin: potent inhibitor of cyclic AMP phosphodiesterase.水飞蓟素：环磷酸腺苷磷酸二酯酶的强效抑制剂。
Methods Find Exp Clin Pharmacol. 1985 Aug;7(8):409-13.
5
[Silymarin--an inhibitor of horseradish peroxidase (author's transl)].
Experientia. 1977 Nov 15;33(11):1417-8. doi: 10.1007/BF01918777.
6
[Peroxidase isoenzymes in cress seedlings (Lepidium sativum L.) and their inhibition by silybin, silydianin and silychristin].
Experientia. 1977 Dec 15;33(12):1568-9. doi: 10.1007/BF01934001.
7
Advances in pharmacological studies of silymarin.
Mem Inst Oswaldo Cruz. 1991;86 Suppl 2:79-85. doi: 10.1590/s0074-02761991000600020.
8
[Changes in erythrocyte shape and volume caused by silymarin].
Arzneimittelforschung. 1978;28(6):1013-7.
9
[Mechanism of silybin action, IV. Structure-action relationship (author's transl)].水飞蓟宾作用机制，IV. 构效关系（作者译）
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10
[Inhibition of the enzyme-catalyzed degradation of indole-3-acetic acid by silybin, dilydianin, and Silychristin (author's transl)].
Planta Med. 1977 Dec;32(4):331-41. doi: 10.1055/s-0028-1097608.

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本文引用的文献

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Oxygenation of unsaturated fatty acids by the vesicular gland of sheep.绵羊精囊泡对不饱和脂肪酸的氧化作用。
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Silymarin, an inhibitor of lipoxygenase.
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Experientia. 1973 Nov 15;29(11):1372. doi: 10.1007/BF01922826.
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Role of prostaglandin endoperoxide PGG2 in inflammatory processes.前列腺素内过氧化物PGG2在炎症过程中的作用。
Nature. 1977 Jan 13;265(5590):170-3. doi: 10.1038/265170a0.