Gendenshteĭn E I, Volkova N D
Biull Eksp Biol Med. 1975 Aug;80(8):69-71.
Experiments were conducted on cats; a study was made of the effect of pharmacological block and stimulation of the adrenergic innervation on the toxicity and the cumulative effect of strophanthine. It was found that anapryline premedication and a preliminary reserpinization increased the strophanthine tolerance and reduced its cumulative effect. Isadrine caused a sharp elevation of the sensitivity to cardiac glycoside, but no cumulation was present in this case.
在猫身上进行了实验；研究了肾上腺素能神经支配的药理阻断和刺激对毒毛花苷毒性及蓄积作用的影响。发现用阿普林定进行术前用药及预先给予利血平可提高对毒毛花苷的耐受性并降低其蓄积作用。异丙肾上腺素引起对强心苷的敏感性急剧升高，但在这种情况下不存在蓄积现象。
