Andiva S, Yera H, Haeghebaert S, Tourte-Schaefer C, Magnaval J F, Dupouy-Camet J
Laboratoire de parasitologie-mycologie, Hôpital Cochin, 27, rue du Faubourg-Saint-Jacques, 75014 Paris.
Ann Biol Clin (Paris). 2002 Jan-Feb;60(1):79-83.
Serology is a helpful test for the diagnosis of human trichinellosis because clinical signs of this disease (fever and myalgias) are non specific. A lot of techniques have been studied but very few are commercialized and have been comparatively evaluated. We report here the performances of 4 commercially available kits: two Elisa tests, one western blot test & one latex agglutination test. The specificity and sensitivity of the different tests were assayed on 60 sera from patients with a proven trichinellosis and on 70 controls. The four tests had a 100% sensitivity. The specificity was of 98.6% for the western blot, of 93% for the latex agglutination test and of 87 & 77% for the two Elisa tests. Cross reactions are mainly observed in patients with other helminthic infections.
