Kaliste E, Linnainmaa M, Meklin T, Nevalainen A
National Laboratory Animal Center, University of Kuopio.
Lab Anim. 2002 Jan;36(1):43-50. doi: 10.1258/0023677021911759.
Besides the well known allergens, several other risk factors may exist for health in a laboratory animal unit. The exposure to these factors may be significant in animal units with poor general or local ventilation systems. Moreover, means to prevent the distribution of airborne contaminants may be limited in animal units housing rabbits or other bigger laboratory animals. Airborne contaminants in conventional laboratory rabbit rooms were sought to evaluate the occupational exposure of animal care personnel. Concentrations of airborne dust, bacteria, fungi, ammonia and endotoxins were measured during 2 days in three phases: before working activities began, during them and afterwards. Both stationary and some personal samples were taken. All of the contaminants sought were found in the rabbit room air. When compared to reported levels in farm animal production areas, the concentrations measured were generally low. However, moderate or high levels of airborne bacteria and fungi were found occasionally during work routines. Airborne contaminants should be considered as a potential occupational health risk for persons working with laboratory animals.
除了众所周知的过敏原外，实验动物单位中可能还存在其他一些影响健康的风险因素。在整体或局部通风系统不佳的动物单位中，接触这些因素的情况可能很严重。此外，在饲养兔子或其他较大实验动物的动物单位中，防止空气传播污染物扩散的手段可能有限。为评估动物饲养人员的职业暴露情况，对传统实验兔舍中的空气传播污染物进行了研究。在三个阶段的两天时间内，测量了空气尘埃、细菌、真菌、氨和内毒素的浓度：工作活动开始前、工作期间和工作结束后。同时采集了固定样本和一些个人样本。在兔舍空气中发现了所有研究的污染物。与报道的农场动物生产区域的水平相比，所测浓度总体较低。然而，在日常工作中偶尔会发现空气中细菌和真菌的浓度处于中度或高水平。空气传播污染物应被视为从事实验动物工作的人员潜在的职业健康风险。
