Grossman Michael D, Miller Donna, Scaff David W, Arcona Steven
Departments of Surgery, St. Lukes Hospital, University of Pennsylvania, Bethlehem, Pennsylvania 18105, USA.
J Trauma. 2002 Feb;52(2):242-6. doi: 10.1097/00005373-200202000-00007.
As the U.S. population ages, the number of geriatric trauma victims will continue to grow. Outcomes are known to be worse for these patients, in large part because of preexisting conditions (PECs). The specific impact of various PECs on outcome in geriatric trauma has not been well studied because of heterogeneous data sets and sample sizes.
We sought to define the impact of clinical variables and PECs on mortality in geriatric trauma by analyzing a large statewide trauma database. We defined geriatric trauma patients as those age > or = 65. Isolated hip fractures were excluded. We used multiple logistic regression to determine the effect of 21 different PECs on 30-day in-hospital mortality.
Data were abstracted from 33,781 patient records. Overall mortality was 7.6%. For each 1-year increase in age beyond age 65, odds of dying after geriatric trauma increased by 6.8% (95% confidence interval, 6.1-7.5%). When presenting vital signs, Glasgow Coma Scale score, and ISS were controlled, PECs with the strongest effect on mortality were hepatic disease (odds ratio [OR], 5.1), renal disease (OR, 3.1), and cancer (OR, 1.8). Chronic steroid use increased the odds of death after geriatric trauma (OR, 1.6), whereas Coumadin therapy did not.
Considered independently, these data are insufficient to allow withdrawal of care, but this information may be a useful component to help in guiding families faced with difficult decisions after geriatric trauma.
随着美国人口老龄化,老年创伤受害者的数量将持续增加。已知这些患者的预后较差,很大程度上是由于存在基础疾病(PECs)。由于数据集和样本量的异质性,各种基础疾病对老年创伤预后的具体影响尚未得到充分研究。
我们试图通过分析一个大型的全州创伤数据库来确定临床变量和基础疾病对老年创伤死亡率的影响。我们将老年创伤患者定义为年龄≥65岁的患者。孤立性髋部骨折被排除在外。我们使用多元逻辑回归来确定21种不同基础疾病对30天院内死亡率的影响。
数据从33781份患者记录中提取。总体死亡率为7.6%。65岁以后,年龄每增加1岁,老年创伤后死亡几率增加6.8%(95%置信区间,6.1 - 7.5%)。在控制生命体征、格拉斯哥昏迷量表评分和损伤严重度评分后,对死亡率影响最大的基础疾病是肝病(比值比[OR],5.1)、肾病(OR,3.1)和癌症(OR,1.8)。长期使用类固醇会增加老年创伤后死亡几率(OR,1.6),而华法林治疗则不会。
单独考虑,这些数据不足以支持停止治疗,但这些信息可能是帮助指导面临老年创伤后艰难决策的家庭的有用组成部分。