Suppr超能文献

心肌梗死患者的兄弟姐妹是否有特定的高血压管理方法?

Do siblings of myocardial infarction patients have a specific management of hypertension?

作者信息

Metzger M-H, Engel S, Hengstenberg C, Schneider A, Stieber J, Doering A, Thorand B, Holmer S, Loewel H

机构信息

GSF-National Research Center for Environment and Health, Institute of Epidemiology, Ingolstaedter Landstrasse 1, D-85764 Neuherberg, Germany.

出版信息

J Hum Hypertens. 2002 Jan;16(1):67-74. doi: 10.1038/sj.jhh.1001296.

Abstract

The aim of this study was to determine whether the management of hypertension differs between siblings of myocardial infarction patients and the general population. Siblings aged 35 to 74 years, unaffected by myocardial infarction, were drawn from the Augsburg Family Heart Study, conducted in 1996-1997 in southern Germany (n = 524). The reference group consisted of participants of the third MONICA population-based survey conducted in 1994-1995 in the same area, who were aged 35 to 74 years and also unaffected by myocardial infarction (n = 3802). Prevalence, awareness, treatment and control of hypertension (defined by blood pressure > or = 140/90 mm Hg or use of antihypertensive medication) were compared between the two groups. The result was that the prevalence of hypertension was higher in the siblings (men: age-adjusted OR = 1.31, 95% CI: 0.99-1.75; women: age-adjusted OR = 1.83, 95% CI: 1.39-2.41). Male hypertensive siblings were more often aware and treated for hypertension than male hypertensives of the reference group whereas the level of awareness and treatment was comparable between female hypertensives of the two groups. In both genders, no difference in the degree of control was shown between hypertensives of the two groups. In conclusion the siblings and their physicians should pay more attention to the family history of myocardial infarction in order to improve the management of hypertension in this high risk group.

摘要

本研究的目的是确定心肌梗死患者的兄弟姐妹与普通人群在高血压管理方面是否存在差异。1996 - 1997年在德国南部进行的奥格斯堡家庭心脏研究中选取了年龄在35至74岁、未患心肌梗死的兄弟姐妹(n = 524)。对照组由1994 - 1995年在同一地区进行的第三次基于人群的莫尼卡调查的参与者组成,他们年龄在35至74岁,也未患心肌梗死(n = 3802)。比较了两组之间高血压(定义为血压≥140/90 mmHg或使用抗高血压药物)的患病率、知晓率、治疗率和控制率。结果显示,兄弟姐妹中高血压的患病率更高(男性:年龄调整后的OR = 1.31,95%CI:0.99 - 1.75;女性:年龄调整后的OR = 1.83,95%CI:1.39 - 2.41)。男性高血压患者的兄弟姐妹比对照组的男性高血压患者更常知晓并接受高血压治疗,而两组女性高血压患者的知晓率和治疗率相当。在两个性别中,两组高血压患者的控制程度均无差异。总之,兄弟姐妹及其医生应更加关注心肌梗死家族史,以改善这一高危人群的高血压管理。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验