Bondarenko L A, Gubina-Vakulik G I
Ross Fiziol Zh Im I M Sechenova. 2001 Dec;87(12):1643-9.
The influence of hypothermal stress (+4 degrees during 3 h) on the ways of serotonin metabolism in pineal gland and its structure has been studied in dynamics on adult male Wistar rats. It has been revealed that melatonin-producing epiphyseal function suffers from phase changes in dynamics of adaptation--significant rising during 15 min. after beginning of the experiment, rehabilitation up to normal--in 30 min, and fast suppressing--in 3 hrs. Suppressing of the functional pineal activity is not due to switched serotonin metabolism with melatonin and new indoles release, but to a partial pinealocytes breaking from their active function.
研究了低温应激（3小时内4℃）对成年雄性Wistar大鼠松果体5-羟色胺代谢途径及其结构的动态影响。结果表明，产生褪黑素的松果体功能在适应动态过程中出现阶段性变化——实验开始后15分钟显著升高，30分钟恢复正常，3小时迅速抑制。功能性松果体活动的抑制并非由于5-羟色胺代谢转换为褪黑素以及新吲哚的释放，而是部分松果体细胞从其活跃功能中脱离所致。
