Sarateanu D E, Ehrengut W
Immun Infekt. 1975 Apr;3(2):86-8.
A serological study of coronaviruses with the OC 43 agent (HI-test) was undertaken in 1000 sera from the population of Hamburg. 32,7% of the sera showed HI=titers between 1 : 8 and 1 : 128. The geometric mean titer (GMT) for the whole group was 1 : 16. The frequency of seropositive reactions was highest in 244 individuals 15 to 24 years old (52,8% positive reactions, GMT 1 : 19) whilst in the older age groups (25-59 years and over 60 years old) the precentage of positive reactors was markedly lower (14,4% and 16,8%, respectively, GMT 1 : 12). Among 131 twelve to 17 years old youngsters, a seroconversion was demonstrated in paired sera in 6,8% with a 4- to 8-fold rise in HI-titer within 8 weeks.
对汉堡市人群的1000份血清进行了冠状病毒OC43株的血清学研究（血凝抑制试验）。32.7%的血清血凝抑制效价在1:8至1:128之间。整个组的几何平均效价（GMT）为1:16。在244名15至24岁的个体中，血清阳性反应频率最高（52.8%为阳性反应，GMT为1:19），而在年龄较大的组（25至59岁及60岁以上）中，阳性反应者的百分比明显较低（分别为14.4%和16.8%，GMT为1:12）。在131名12至17岁的青少年中，6.8%的配对血清出现血清转化，8周内血凝抑制效价升高4至8倍。
