Kadioglu D, Harrison R G
J Anat. 1975 Sep;120(Pt 1):179-89.
Ultrastructurally, the adrenal cortex of the Mongolian gerbil can be divided into two main regions and one narrow interposed border zone. The outer region corresponds to the zona glomerulosa and zona fasciculata of the rat adrenal cortex, whereas the inner region corresponds to the rat zona reticularis. The mitochondria are variable in shape, size and internal structure but generally lamelliform or tubulo-vesicular with a dense matrix in the outer region and plate-like and tubular in the inner region. Some of the mitochondria in the border region are of the polylaminar membranous type. The endoplasmic reticulum is abundant and smooth in the outer region but less prominent in the inner regions, where it is both smooth and rough. The concentric whorled membranes of rough endoplasmic reticulum are a characteristic feature of the border zone. Lipid vacuoles are abundant in the outer region. Lysosomes are numerous in the inner region and tend to form groups of 4 or 5. Aminoglutethimide causes a less conspicuous alteration in the adrenal cortex of the Mongolian gerbil than in the rat. The main alterations consist of a profound increase of lipid and lysosomes, a decrease in the number of SER profiles, and complete disappearance of the whorled membranes of RER.
在超微结构上，蒙古沙鼠的肾上腺皮质可分为两个主要区域和一个狭窄的中间边界区。外部区域对应于大鼠肾上腺皮质的球状带和束状带，而内部区域对应于大鼠的网状带。线粒体的形状、大小和内部结构各不相同，但在外部区域通常呈层状或管状泡状，基质致密，在内部区域呈板状和管状。边界区域的一些线粒体是多层膜型。内质网在外部区域丰富且光滑，但在内部区域不太明显，内部区域既有光滑型也有粗糙型。粗糙内质网的同心螺旋膜是边界区的一个特征。脂质空泡在外部区域丰富。溶酶体在内部区域众多，倾向于形成4或5个的群体。氨鲁米特对蒙古沙鼠肾上腺皮质的改变比对大鼠的改变不那么明显。主要改变包括脂质和溶酶体的显著增加、滑面内质网轮廓数量的减少以及粗面内质网螺旋膜的完全消失。
