Rice P A, Boehm G W, Moynihan J A, Bellinger D L, Stevens S Y
Department of Environmental Medicine, University of Rochester School of Medicine, New York 14642, USA.
Brain Behav Immun. 2002 Feb;16(1):62-73. doi: 10.1006/brbi.2000.0611.
Sympathectomy of BALB/c mice that were injected with either Listeria monocytogenes or saline did not affect the total number of splenic leukocytes measured 1-3 days after injection, but sympathectomy did increase the percentages of neutrophils in the spleens of both infected and uninfected mice. By contrast, sympathectomy was associated with increased numbers of peritoneal exudate cells (PEC) and peritoneal macrophages in both groups of mice. Sympathectomy did not affect tumor necrosis factor-alpha, interleukin-12, or interferon-gamma production in cultured splenocytes or PEC in either infected or uninfected mice.
对注射了单核细胞增生李斯特菌或生理盐水的BALB/c小鼠进行交感神经切除术，并不影响注射后1 - 3天测量的脾脏白细胞总数，但交感神经切除术确实增加了感染和未感染小鼠脾脏中中性粒细胞的百分比。相比之下，交感神经切除术与两组小鼠腹腔渗出细胞（PEC）和腹腔巨噬细胞数量增加有关。交感神经切除术对感染或未感染小鼠培养的脾细胞或PEC中肿瘤坏死因子-α、白细胞介素-12或干扰素-γ的产生没有影响。
