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化学性交感神经切除术在小鼠李斯特菌病早期会增加腹膜中炎症细胞的数量。

Chemical sympathectomy increases numbers of inflammatory cells in the peritoneum early in murine listeriosis.

作者信息

Rice P A, Boehm G W, Moynihan J A, Bellinger D L, Stevens S Y

机构信息

Department of Pulmonary and Critical Care Medicine, University of Maryland, 3C116, VAMC 10 N. Greene Street, Baltimore, MD 21201, USA.

出版信息

Brain Behav Immun. 2002 Dec;16(6):654-62. doi: 10.1016/s0889-1591(02)00016-8.

DOI:10.1016/s0889-1591(02)00016-8
PMID:12480496
Abstract

Here, we investigated the effects of sympathectomy on systemic bacterial loads following infection with Listeria monocytogenes, and on innate and specific immune responses in the peritoneum. Sympathectomy decreased systemic bacterial loads, and increased the number of peritoneal leukocytes and the percentage of peritoneal macrophages three days postinfection. This suggests that sympathectomy-induced decreases systemic bacterial loads are associated with increased recruitment of inflammatory cells into tissues during the innate immune response.

摘要

在此,我们研究了去交感神经术对感染单核细胞增生李斯特菌后全身细菌载量的影响,以及对腹膜固有免疫和特异性免疫反应的影响。去交感神经术降低了全身细菌载量,并在感染后三天增加了腹膜白细胞数量和腹膜巨噬细胞百分比。这表明去交感神经术引起的全身细菌载量降低与固有免疫反应期间炎症细胞向组织中的募集增加有关。

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Chemical sympathectomy increases numbers of inflammatory cells in the peritoneum early in murine listeriosis.化学性交感神经切除术在小鼠李斯特菌病早期会增加腹膜中炎症细胞的数量。
Brain Behav Immun. 2002 Dec;16(6):654-62. doi: 10.1016/s0889-1591(02)00016-8.
2
Chemical sympathectomy increases the innate immune response and decreases the specific immune response in the spleen to infection with Listeria monocytogenes.化学性交感神经切除术增强了先天性免疫反应,并降低了脾脏对单核细胞增生李斯特菌感染的特异性免疫反应。
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Chemical sympathectomy alters numbers of splenic and peritoneal leukocytes.化学性交感神经切除术会改变脾脏和腹膜白细胞的数量。
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Effect of 6-hydroxydopamine on host resistance against Listeria monocytogenes infection.6-羟基多巴胺对宿主抵抗单核细胞增生李斯特菌感染的影响。
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CD69 limits early inflammatory diseases associated with immune response to Listeria monocytogenes infection.CD69 限制与李斯特菌感染的免疫反应相关的早期炎症性疾病。
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Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis.干扰素共有序列结合蛋白的关键作用,但干扰素调节因子1和一氧化氮合成在抵抗小鼠李斯特菌病方面均无此作用。
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The effects of chemical sympathectomy on T-cell cytokine responses are not mediated by altered peritoneal exudate cell function or an inflammatory response.化学性交感神经切除术对T细胞细胞因子反应的影响并非由腹膜渗出细胞功能改变或炎症反应介导。
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Sympathetic nervous system plays a major role in acute cold/restraint stress inhibition of host resistance to Listeria monocytogenes.交感神经系统在急性寒冷/束缚应激抑制宿主对单核细胞增生李斯特菌的抵抗力中起主要作用。
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Neutrophils are involved in the non-specific resistance to listeriosis induced by mycobacterial infections.中性粒细胞参与了由分枝杆菌感染引起的李斯特菌病的非特异性抵抗。
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Metastatic Listeria monocytogenes infection of the peritoneum in mice with cyclosporine a-induced peritonitis.环孢素A诱导的腹膜炎小鼠腹膜的单核细胞增生李斯特菌转移性感染
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