Buist Michael D, Moore Gaye E, Bernard Stephen A, Waxman Bruce P, Anderson Jeremy N, Nguyen Tuan V
Department of Intensive Care, Dandenong Hospital, Dandenong, VIC 3175, Australia.
BMJ. 2002 Feb 16;324(7334):387-90. doi: 10.1136/bmj.324.7334.387.
To determine whether earlier clinical intervention by a medical emergency team prompted by clinical instability in a patient could reduce the incidence of and mortality from unexpected cardiac arrest in hospital.
A non-randomised, population based study before (1996) and after (1999) introduction of the medical emergency team.
300 bed tertiary referral teaching hospital.
All patients admitted to the hospital in 1996 (n=19 317) and 1999 (n=22 847).
Medical emergency team (two doctors and one senior intensive care nurse) attended clinically unstable patients immediately with resuscitation drugs, fluid, and equipment. Response activated by the bedside nurse or doctor according to predefined criteria.
Incidence and outcome of unexpected cardiac arrest.
The incidence of unexpected cardiac arrest was 3.77 per 1000 hospital admissions (73 cases) in 1996 (before intervention) and 2.05 per 1000 admissions (47 cases) in 1999 (after intervention), with mortality being 77% (56 patients) and 55% (26 patients), respectively. After adjustment for case mix the intervention was associated with a 50% reduction in the incidence of unexpected cardiac arrest (odds ratio 0.50, 95% confidence interval 0.35 to 0.73).
In clinically unstable inpatients early intervention by a medical emergency team significantly reduces the incidence of and mortality from unexpected cardiac arrest in hospital.
确定由患者临床不稳定状况引发的医疗急救团队更早进行临床干预是否能降低医院内意外心脏骤停的发生率和死亡率。
在引入医疗急救团队之前(1996年)和之后(1999年)进行的一项基于人群的非随机研究。
一家拥有300张床位的三级转诊教学医院。
1996年(n = 19317)和1999年(n = 22847)入院的所有患者。
医疗急救团队(两名医生和一名高级重症监护护士)立即携带复苏药物、液体和设备对临床不稳定的患者进行救治。由床边护士或医生根据预定义标准启动响应。
意外心脏骤停的发生率和结局。
1996年(干预前)意外心脏骤停的发生率为每1000例住院患者3.77例(73例),1999年(干预后)为每1000例住院患者2.05例(47例),死亡率分别为77%(56例患者)和55%(26例患者)。在对病例组合进行调整后,干预措施使意外心脏骤停的发生率降低了50%(比值比0.50,95%置信区间0.35至0.73)。
对于临床不稳定的住院患者,医疗急救团队的早期干预可显著降低医院内意外心脏骤停的发生率和死亡率。