Whence interferon? Variety in the production of interferon in response to viral infection.
作者信息
Levy David E
机构信息
Molecular Oncology and Immunology Program, Department of Pathology, Kaplan Comprehensive Cancer Center, New York University School of Medicine, 550 First Ave., New York, NY 10016, USA.
出版信息
J Exp Med. 2002 Feb 18;195(4):F15-8. doi: 10.1084/jem.20020075.
Abstract
摘要
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Promotion of alpha/beta interferon induction during in vivo viral infection through alpha/beta interferon receptor/STAT1 system-dependent and -independent pathways.通过α/β干扰素受体/STAT1系统依赖性和非依赖性途径促进体内病毒感染期间的α/β干扰素诱导。
J Virol. 2002 May;76(9):4520-5. doi: 10.1128/jvi.76.9.4520-4525.2002.
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Interferon alpha/beta and interleukin 12 responses to viral infections: pathways regulating dendritic cell cytokine expression in vivo.干扰素α/β和白细胞介素12对病毒感染的反应：体内调节树突状细胞细胞因子表达的途径
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3
Virus-induced interferon alpha production by a dendritic cell subset in the absence of feedback signaling in vivo.在体内缺乏反馈信号的情况下，树突状细胞亚群由病毒诱导产生α干扰素。
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Enhancement and diversification of IFN induction by IRF-7-mediated positive feedback.通过IRF-7介导的正反馈增强和多样化干扰素诱导
J Interferon Cytokine Res. 2002 Jan;22(1):87-93. doi: 10.1089/107999002753452692.
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Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway.小型抗病毒化合物通过TLR7 MyD88依赖性信号通路激活免疫细胞。
Nat Immunol. 2002 Feb;3(2):196-200. doi: 10.1038/ni758. Epub 2002 Jan 22.
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Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology.小鼠I型干扰素产生细胞是具有浆细胞样形态的未成熟抗原呈递细胞。
Nat Immunol. 2001 Dec;2(12):1144-50. doi: 10.1038/ni736.
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Lymphotoxins and cytomegalovirus cooperatively induce interferon-beta, establishing host-virus détente.淋巴毒素和巨细胞病毒协同诱导β干扰素，建立宿主与病毒的缓和状态。
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IFNs activate toll-like receptor gene expression in viral infections.干扰素在病毒感染中激活Toll样受体基因表达。
Genes Immun. 2001 Oct;2(6):349-55. doi: 10.1038/sj.gene.6363791.
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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3.Toll样受体3对双链RNA的识别及NF-κB的激活
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CD11c(+)B220(+)Gr-1(+) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells.小鼠淋巴结和脾脏中的CD11c(+)B220(+)Gr-1(+)细胞表现出浆细胞样树突状细胞的特征。
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