Scott Ingrid U, Feuer William J, Jacko Julie A
Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami School of Medicine, Miami, Florida 33101, USA.
Am J Ophthalmol. 2002 Mar;133(3):350-7. doi: 10.1016/s0002-9394(01)01406-4.
To investigate the impact of visual function parameters on computer task performance in patients with age-related macular degeneration (AMD).
Interventional case series.
Eighteen patients with visual impairment due to age-related macular degeneration underwent evaluation of visual acuity using the Early Treatment Diabetic Retinopathy Study protocol, contrast sensitivity using a Pelli-Robson chart, binocular simultaneous visual field using the Esterman program on an automated perimeter, and color vision using Farnsworth D-15. Each subject then completed 125 computer icon identification tasks. Relationships between computer task performance (accuracy and speed) and visual function parameters (visual acuity, contrast sensitivity, visual field, and color vision) were analyzed.
Visual acuity and contrast sensitivity in the better eye, weighted average contrast sensitivity, and color vision defects are significantly associated with computer task accuracy. Visual acuity in the better eye, weighted average visual acuity, and color vision defects are significantly associated with performance speed. Visual function parameters and clinical features significantly associated with computer task accuracy in a multiple regression model include weighted average contrast sensitivity (P = 0.001), protan color vision defect (P = 0.002), cataract severity in the better-seeing eye (P = 0.036), and geographic atrophy outside the central macula (P = 0.046). Visual function parameters and clinical features significantly associated with computer task speed in a multiple regression model include color vision defects (deutan, P < 0.001; protan, P < 0.001) and gender (P = 0.05).
Among this cohort of patients with AMD, visual acuity, contrast sensitivity, and color vision defects are significant predictors of computer task performance. Visual function parameters of the better eye played a more significant role than parameters of the worse eye, and contrast sensitivity is the most significant predictor of computer task accuracy.
研究年龄相关性黄斑变性（AMD）患者的视觉功能参数对计算机任务表现的影响。
干预性病例系列研究。
18例因年龄相关性黄斑变性导致视力受损的患者，按照早期糖尿病视网膜病变研究方案进行视力评估，使用贝利-罗布森图表评估对比敏感度，在自动视野计上采用埃斯特曼程序评估双眼同时视野，使用法恩斯沃思D-15评估色觉。然后，每位受试者完成125项计算机图标识别任务。分析计算机任务表现（准确性和速度）与视觉功能参数（视力、对比敏感度、视野和色觉）之间的关系。
较好眼的视力和对比敏感度、加权平均对比敏感度以及色觉缺陷与计算机任务准确性显著相关。较好眼的视力、加权平均视力以及色觉缺陷与表现速度显著相关。在多元回归模型中，与计算机任务准确性显著相关的视觉功能参数和临床特征包括加权平均对比敏感度（P = 0.001）、红色盲色觉缺陷（P = 0.002）、较好眼的白内障严重程度（P = 0.036）以及黄斑中心凹外的地图样萎缩（P = 0.046）。在多元回归模型中，与计算机任务速度显著相关的视觉功能参数和临床特征包括色觉缺陷（绿色盲，P < 0.001；红色盲，P < 0.001）和性别（P = 0.05）。
在该队列AMD患者中，视力、对比敏感度和色觉缺陷是计算机任务表现的重要预测因素。较好眼的视觉功能参数比较差眼的参数发挥更显著的作用，对比敏感度是计算机任务准确性的最显著预测因素。
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