Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
PLoS One. 2020 May 19;15(5):e0233295. doi: 10.1371/journal.pone.0233295. eCollection 2020.
Epiphora causes deterioration in contrast sensitivity in some eye diseases. This study was conducted to investigate contrast sensitivity in eyes with epiphora caused by lacrimal passage obstruction.
This single-center, prospective case series enrolled 57 patients with unilateral lacrimal passage obstruction. The best-corrected visual acuity (BCVA), contrast sensitivity function, and lower tear meniscus of the affected and contralateral unaffected eyes were compared. The area under the log contrast sensitivity function (AULCSF) was calculated.
The BCVA did not significantly differ between the affected and contralateral eyes, while the AULCSF was significantly lower in the affected eyes than that in the contralateral eyes (median 1.35, interquartile range 1.22-1.44 vs. median 1.36, interquartile range 1.28-1.46, P = 0.032). Lower tear meniscus parameters were significantly higher in the affected eyes than those in the contralateral eyes (P < 0.005).
The contrast sensitivity function is significantly diminished in eyes with epiphora caused by lacrimal passage obstruction.
溢泪可导致某些眼病的对比敏感度下降。本研究旨在探讨因泪道阻塞所致溢泪的眼的对比敏感度。
本单中心前瞻性病例系列研究纳入了 57 例单侧泪道阻塞患者。比较了患眼和对侧未受影响眼的最佳矫正视力（BCVA）、对比敏感度功能和下泪膜弯月面。计算了对数对比敏感度函数的曲线下面积（AULCSF）。
患眼与对侧眼的 BCVA 无显著差异，而患眼的 AULCSF 明显低于对侧眼（中位数 1.35，四分位距 1.22-1.44 与中位数 1.36，四分位距 1.28-1.46，P=0.032）。患眼的下泪膜弯月面参数明显高于对侧眼（P<0.005）。
因泪道阻塞所致溢泪的眼的对比敏感度功能明显降低。
