Meyer Carsten H, Lapolice Deborah J, Freedman Sharon F
Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina 27710, USA.
Am J Ophthalmol. 2002 Mar;133(3):409-10. doi: 10.1016/s0002-9394(01)01326-5.
To document, in vivo, the foveal morphology and thickness in a patient with oculocutaneous albinism.
Observational case report. In a 10-year-old female with oculocutaneous albinism, multiple cross-sectional scans of the fovea were performed using optical coherence tomography.
Optical coherence tomography scans were unable to detect the foveal pit. A widespread thickening of the retina occurred throughout the entire fovea with no difference from the surrounding macula. The foveal thickness was greater than 300 microm in the eyes of this patient with oculocutaneous albinism, compared with 150 microm in the normal eye. The inner retina had a highly reflective signal on optical coherence tomography.
Optical coherence tomography demonstrated in the anatomical location of the fovea a highly reflective inner retinal signal, possibly consistent with multiple layers of ganglion cells, and it confirmed foveal hypoplasia in a patient with oculocutaneous albinism.
在活体中记录一名眼皮肤白化病患者的黄斑中心凹形态和厚度。
观察性病例报告。对一名10岁眼皮肤白化病女性患者的黄斑中心凹进行多次光学相干断层扫描。
光学相干断层扫描无法检测到黄斑中心凹凹陷。整个黄斑中心凹出现广泛的视网膜增厚,与周围黄斑无差异。该眼皮肤白化病患者的黄斑中心凹厚度大于300微米,而正常眼为150微米。光学相干断层扫描显示视网膜内层有高反射信号。
光学相干断层扫描在黄斑中心凹的解剖位置显示出视网膜内层的高反射信号,可能与多层神经节细胞一致,并证实了一名眼皮肤白化病患者存在黄斑发育不全。