Fragiotta Serena, Ciancimino Chiara, Perdicchi Andrea, de Paula Alessandro, Abdolrahimzadeh Solmaz, Scuderi Gianluca
Ophthalmology Unit, Department of Neurosciences, Mental Health, and Sensory Organs (NESMOS), St. Andrea Hospital, University of Rome "La Sapienza", Rome, Italy.
Azienda Ospedaliera San Giovanni-Addolorata, Rome, Italy.
Front Neurol. 2021 Apr 27;12:633492. doi: 10.3389/fneur.2021.633492. eCollection 2021.
This paper aims to study adaptative vascular arrangements in idiopathic fovea plana with volume-rendered optical coherence tomography angiography (OCTA). A retrospective review of two cases of idiopathic fovea plana (mean age: 26.5 years) and two age-matched controls imaged with OCTA was conducted using spectral-domain OCTA (RTVue XR Avanti, Optovue, Inc., Fremont, CA) equipped with the AngioVue software. Both en face OCTA slabs and OCTA b scans were processed through Fiji software (http://fiji.sc; software version 2.0.0-rc-68/1.52e), and then extracted as image sequences for volume rendering reconstructions using the ImageVis3D volume rendering system (3.1.0 release). Eyes with idiopathic fovea plana demonstrated a regular superficial vascular plexus connecting to a single vascular monolayer representing the deeper vascular plexuses. At this location, several vertical short path connections were demonstrated, in contraposition with normal eyes where short path connections were infrequently observed. Advances in three-dimensional OCTA reconstruction increase the understanding of vascular connections and arrangement in retinal plexuses and possible anatomical variations that cannot be detected with conventional two-dimensional b scans.
本文旨在利用容积渲染光学相干断层扫描血管造影（OCTA）研究特发性扁平黄斑的适应性血管排列。使用配备AngioVue软件的光谱域OCTA（RTVue XR Avanti，Optovue公司，弗里蒙特，加利福尼亚）对2例特发性扁平黄斑患者（平均年龄：26.5岁）和2例年龄匹配的对照者进行了回顾性成像研究。通过Fiji软件（http://fiji.sc；软件版本2.0.0 - rc - 68/1.52e）处理正面OCTA层和OCTA B扫描，然后提取为图像序列，使用ImageVis3D容积渲染系统（3.1.0版本）进行容积渲染重建。特发性扁平黄斑的眼睛表现出规则的浅表血管丛连接到代表较深血管丛的单个血管单层。在这个位置，显示出几条垂直的短路径连接，这与正常眼睛中很少观察到短路径连接形成对比。三维OCTA重建技术的进步增进了我们对视网膜丛中血管连接和排列以及传统二维B扫描无法检测到的可能解剖变异的理解。
