Saito Yoshiaki, Saito Kayoko, Hirano Yukiko, Ikeya Kiyoko, Suzuki Haruko, Shishikura Keiko, Manno Sumie, Takakuwa Yuichi, Nakagawa Kiyoshi, Iwasa Aiko, Fujikawa Satoshi, Moriya Makoto, Mizoguchi Nobuyuki, Golden Barbara E, Osawa Makiko
Department of Pediatrics, Institute of Rheumatology, Tokyo Women's Medical University (TWMU), Japan.
J Pediatr. 2002 Feb;140(2):267-9. doi: 10.1067/mpd.2002.121699.
A boy had infantile-onset systemic inflammation, growth failure, hepatosplenomegaly, anemia, leukocytopenia, progressive muscular dystrophy, and hypercalprotectinemia, resulting in marked hyperzincemia. His mother had a history of chronic arthritis since childhood and also showed hypercalprotectinemia/hyperzincemia. We postulate an inherent defect in calprotectin metabolism.
一名男孩患有婴儿期全身性炎症、生长发育迟缓、肝脾肿大、贫血、白细胞减少、进行性肌肉营养不良以及高钙卫蛋白血症，导致明显的高锌血症。他的母亲自幼有慢性关节炎病史，也表现出高钙卫蛋白血症/高锌血症。我们推测钙卫蛋白代谢存在内在缺陷。
