Barkhausen Jörg, Goyen Mathias, von Winterfeld Friederike, Lauenstein Thomas, Arweiler-Harbeck Diana, Debatin Jörg F
Department of Diagnostic Radiology, University Hospital Essen, Hufelandstrasse 55, 45122 Essen, Germany.
Eur Radiol. 2002 Jan;12(1):129-33. doi: 10.1007/s00330-001-1146-8. Epub 2001 Oct 13.
The aim of this study was to evaluate the ability of different real-time true fast imaging with steady precession (TrueFISP) sequences regarding their ability to depict the swallowing process and delineate oropharyngeal pathologies in patients with dysphagia. Real-time TrueFISP visualization of swallowing was performed in 8 volunteers and 6 patients with dysphagia using a 1.5 T scanner (Magnetom Sonata, Siemens, Erlangen Germany) equipped with high-performance gradients (amplitude 40 mT/m). Image quality of four different real-time TrueFISP sequences (TR 2.2-3.0 ms, TE 1.1-1.5 ms, matrix 63 x 128-135 x 256, field of view 250 mm(2), acquisition time per image 139-405 ms) was evaluated. Water, yoghurt, and semolina pudding were assessed as oral contrast agents. Functional exploration of the oropharyngeal apparatus was best possible using the fastest real-time TrueFISP sequence (TR 2.2 ms, TE 1.1 ms, matrix 63 x 128). Increased acquisition time resulted in blurring of anatomical structures. As the image contrast of TrueFISP sequences depends on T2/T1 properties, all tested foodstuff were well suited as oral contrast agents, but image quality was best using semolina pudding. Real-time visualization of swallowing is possible using real-time TrueFISP sequences in conjunction with oral contrast agents. For the functional exploration of swallowing high temporal resolution is more crucial than spatial resolution.
本研究的目的是评估不同的实时稳态进动快速成像（TrueFISP）序列描绘吞咽过程以及识别吞咽困难患者口咽病变的能力。使用配备高性能梯度（振幅40 mT/m）的1.5 T扫描仪（德国西门子公司埃尔兰根市生产的Magnetom Sonata），对8名志愿者和6名吞咽困难患者进行了吞咽的实时TrueFISP可视化检查。评估了四种不同实时TrueFISP序列（重复时间2.2 - 3.0 ms，回波时间1.1 - 1.5 ms，矩阵63×128 - 135×256，视野250 mm²，每幅图像采集时间139 - 405 ms）的图像质量。水、酸奶和粗粒小麦粉布丁被用作口服对比剂进行评估。使用最快的实时TrueFISP序列（重复时间2.2 ms，回波时间1.1 ms，矩阵63×128）能够最佳地对口咽结构进行功能探查。采集时间增加会导致解剖结构模糊。由于TrueFISP序列的图像对比度取决于T2/T1特性，所有测试的食物都非常适合作为口服对比剂，但使用粗粒小麦粉布丁时图像质量最佳。使用实时TrueFISP序列结合口服对比剂能够实现吞咽的实时可视化。对于吞咽功能探查而言，高时间分辨率比空间分辨率更为关键。
