Mieli-Vergani Giorgina, Vergani Diego
Department of Child Health, King's College Hospital, Denmark Hill.
Indian J Pediatr. 2002 Jan;69(1):93-8. doi: 10.1007/BF02723785.
Autoimmune liver disorders are inflammatory liver diseases characterised histologically by a dense mononuclear cell infiltrate in the portal tract and serologically by the presence of non-organ and liver specific autoantibodies and increased levels of immunoglobulin G (IgG), in the absence of a known etiology. They usually respond to immunosuppressive treatment, which should be instituted as soon as diagnosis is made. The onset is variable and often mimics acute hepatitis. The previously accepted requirement of six month duration of symptoms before a diagnosis of autoimmune disease could be made has been abandoned.
自身免疫性肝病是一种炎症性肝病，组织学特征为门静脉区有密集的单核细胞浸润，血清学特征为存在非器官特异性和肝脏特异性自身抗体以及免疫球蛋白G（IgG）水平升高，且无已知病因。它们通常对免疫抑制治疗有反应，一旦确诊就应立即开始治疗。其发病情况多样，常类似急性肝炎。以前认为在诊断自身免疫性疾病之前症状需持续六个月的要求已被摒弃。
