Kudo Koji, Yoshida Masafumi, Makishima Kazumi
Department of Otorhinolaryngology, University of Occupational and Environmental Health, School of Medicine, Kitakyushu, Japan.
Acta Otolaryngol. 2002 Jan;122(1):37-42. doi: 10.1080/00016480252775715.
Gaze fixation during optokinetic stimulation generates an after-nystagmus with a slow component towards the reverse direction of the optokinetic stimulation. The duration and maximum slow component velocity (SCV) of this "reverse OKAN" were observed by changing the duration, velocity and direction of the optokinetic stimulation in nine normal volunteers. The duration of reverse OKAN increased with increasing stimulation time but was unaffected by changes in the stimulation velocity. The maximum SCV of reverse OKAN decreased with an increase in the stimulation velocity but was not significantly affected by changes in the optokinetic stimulation time. There was no directional difference among the horizontal, upwards and downwards reverse OKANs. The reverse OKAN was thought to be generated by a mechanism different from the velocity storage mechanism which produced optokinetic nystagmus and the first phase of OKAN. Retinal slip during the optokinetic stimulation was considered to be an input to the mechanism which generated the reverse OKAN. We hypothesize that the mechanism causing the reverse OKAN may be a generator of the second phase of OKAN, which was also intimately connected with self-motion sensation during the optokinetic stimulation.
视动刺激期间的注视会产生一种眼震后效，其慢相朝向视动刺激的相反方向。通过改变九名正常志愿者视动刺激的持续时间、速度和方向，观察了这种“反向视动性眼震后效（reverse OKAN）”的持续时间和最大慢相速度（SCV）。反向OKAN的持续时间随刺激时间的增加而增加，但不受刺激速度变化的影响。反向OKAN的最大SCV随刺激速度的增加而降低，但视动刺激时间的变化对其影响不显著。水平、向上和向下的反向OKAN之间没有方向差异。反向OKAN被认为是由一种与产生视动性眼震和视动性眼震后效第一阶段的速度存储机制不同的机制产生的。视动刺激期间的视网膜滑动被认为是产生反向OKAN的机制的一种输入。我们假设，导致反向OKAN的机制可能是视动性眼震后效第二阶段的发生器，它也与视动刺激期间的自我运动感觉密切相关。
