民航机组人员的血清抗氧化状态

Serum antioxidant status of civil aircrew.

作者信息

Liu J K, Chen W R, Zhang H L, Feng Y J, Li H, Zhang Y, Guo Y, Duan S Y, Peng X T, Sun T P, Jia B S

机构信息

Nankai University School of Medicine, Tianjin, China.

出版信息

Space Med Med Eng (Beijing). 2001 Jun;14(3):157-61.

PMID:11890182

Abstract

Objective. To study the serum antioxidant status in civil aircrew members who had more than 4000 h of cumulative flight hours, therefore exposed to a higher dose of cosmic radiation comparing to the dose received by ground residents. Method. Differences in the serum levels of total antioxidant capacity (TAOC), superoxide dismutase (SOD) and malondialdehyde (MDA) were investigated in 230 crew members, 37 local ground residents in Xinjiang, and 37 ground residents in Tianjin. Result. Significantly higher levels of all the three serum indexes were found in civil aircrew members. Serum levels of TAOC and SOD were higher in Xinjiang than in Tianjin ground residents, although no difference was found for MDA. Positive correlations were observed among the three serum indexes in this study. Conclusion. The elevated serum level of MDA in civil aircrew members deserves a proper attention by health care policy makers.

摘要

目的。研究累计飞行时长超过4000小时的民航机组人员的血清抗氧化状态，因此与地面居民相比，他们受到更高剂量的宇宙辐射。方法。对230名机组人员、37名新疆当地地面居民和37名天津地面居民的血清总抗氧化能力（TAOC）、超氧化物歧化酶（SOD）和丙二醛（MDA）水平差异进行了研究。结果。民航机组人员的所有三项血清指标水平均显著更高。新疆地面居民的TAOC和SOD血清水平高于天津地面居民，尽管MDA未发现差异。本研究中三项血清指标之间存在正相关。结论。民航机组人员血清MDA水平升高值得卫生保健政策制定者给予适当关注。