Virant F S
Northwest Asthma & Allergy Center, University of Washington, 4540 Sand Point Way NE, Seattle, WA 98105, USA.
Curr Allergy Asthma Rep. 2001 May;1(3):277-81. doi: 10.1007/s11882-001-0019-1.
Sinusitis and asthma often coexist in patients. In fact, these airways disorders are similar histologically, with tissue eosinophils, increased glandular tissue, and edema. Medical or surgical therapy for sinusitis often greatly improves asthma, suggesting that sinusitis may exacerbate asthma. Possible mechanisms by which asthma could be worsened by sinus disease include neural reflex pathways and interference with the important nasal functions of heating, humidification, and filtration. Health professionals treating asthmatic patients should consider sinusitis as a possible underlying cause, in addition to other triggers (e.g., allergic rhinitis and gastroesophageal reflux disease).
鼻窦炎和哮喘在患者中常常同时存在。事实上，这些气道疾病在组织学上相似，都有组织嗜酸性粒细胞、腺组织增多和水肿。鼻窦炎的药物或手术治疗常常能显著改善哮喘，这表明鼻窦炎可能会加重哮喘。鼻窦疾病可能使哮喘恶化的机制包括神经反射途径以及对鼻腔加热、加湿和过滤等重要功能的干扰。治疗哮喘患者的医护人员除了考虑其他诱发因素（如过敏性鼻炎和胃食管反流病）外，还应将鼻窦炎视为可能的潜在病因。
