Levetin E, Van de Water P
Faculty of Biological Science, University of Tulsa, 304 Oliphant Hall, Tulsa, OK 74104, USA.
Curr Allergy Asthma Rep. 2001 Nov;1(6):506-14. doi: 10.1007/s11882-001-0059-6.
The environment is a major contributor to allergic disease, and great effort is being expended to identify the chemical pollutants and allergens that make a significant impact. Exposure to high levels of ozone, sulfur dioxide, nitrogen dioxide, and diesel exhaust particles is known to reduce lung function. Studies continue to delineate the role of these particles as adjuvants and carriers of allergens into the respiratory system. Current studies also show the exacerbation of allergic disease through fungal spore inhalation and continue to document the role of pollen in allergic rhinitis. Pollen also was recently associated with asthma epidemics, especially after thunderstorms. Forecasting models currently are being developed that predict the trajectories of pollen dispersal and may allow increased avoidance of dangerous outdoor conditions.
环境是导致过敏性疾病的主要因素,人们正在付出巨大努力来识别那些产生重大影响的化学污染物和过敏原。已知暴露于高浓度的臭氧、二氧化硫、二氧化氮和柴油废气颗粒会降低肺功能。研究不断阐明这些颗粒作为过敏原的佐剂和载体进入呼吸系统的作用。目前的研究还表明,吸入真菌孢子会加剧过敏性疾病,并不断证明花粉在过敏性鼻炎中的作用。花粉最近还与哮喘流行有关,尤其是在雷暴之后。目前正在开发预测模型,以预测花粉传播轨迹,这可能有助于人们更多地避免危险的户外环境。