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环境对过敏性疾病的影响。

Environmental contributions to allergic disease.

作者信息

Levetin E, Van de Water P

机构信息

Faculty of Biological Science, University of Tulsa, 304 Oliphant Hall, Tulsa, OK 74104, USA.

出版信息

Curr Allergy Asthma Rep. 2001 Nov;1(6):506-14. doi: 10.1007/s11882-001-0059-6.

DOI:10.1007/s11882-001-0059-6
PMID:11892080
Abstract

The environment is a major contributor to allergic disease, and great effort is being expended to identify the chemical pollutants and allergens that make a significant impact. Exposure to high levels of ozone, sulfur dioxide, nitrogen dioxide, and diesel exhaust particles is known to reduce lung function. Studies continue to delineate the role of these particles as adjuvants and carriers of allergens into the respiratory system. Current studies also show the exacerbation of allergic disease through fungal spore inhalation and continue to document the role of pollen in allergic rhinitis. Pollen also was recently associated with asthma epidemics, especially after thunderstorms. Forecasting models currently are being developed that predict the trajectories of pollen dispersal and may allow increased avoidance of dangerous outdoor conditions.

摘要

环境是导致过敏性疾病的主要因素,人们正在付出巨大努力来识别那些产生重大影响的化学污染物和过敏原。已知暴露于高浓度的臭氧、二氧化硫、二氧化氮和柴油废气颗粒会降低肺功能。研究不断阐明这些颗粒作为过敏原的佐剂和载体进入呼吸系统的作用。目前的研究还表明,吸入真菌孢子会加剧过敏性疾病,并不断证明花粉在过敏性鼻炎中的作用。花粉最近还与哮喘流行有关,尤其是在雷暴之后。目前正在开发预测模型,以预测花粉传播轨迹,这可能有助于人们更多地避免危险的户外环境。

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本文引用的文献

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Respiratory effects of seasonal exposures to ozone and particles.季节性暴露于臭氧和颗粒物对呼吸系统的影响。
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The importance of allergens in the development of asthma and the persistence of symptoms.变应原在哮喘发病及症状持续存在中的重要性。
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4
Expulsion of allergen-containing materials from hydrated rye grass (Lolium perenne) pollen revealed by using immunogold field emission scanning and transmission electron microscopy.利用免疫金场发射扫描和透射电子显微镜揭示了水合黑麦草(多年生黑麦草)花粉中含过敏原物质的排出情况。
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Is allergen exposure the major primary cause of asthma?过敏原暴露是哮喘的主要原发性病因吗?
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The relevance of allergen exposure to the development of asthma in childhood.变应原暴露与儿童哮喘发生的相关性。
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Increased specific airway reactivity of persons with mild allergic asthma after 7.6 hours of exposure to 0.16 ppm ozone.轻度过敏性哮喘患者在暴露于0.16 ppm臭氧7.6小时后气道特异性反应性增加。
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