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气候变化对过敏性哮喘影响的预测:空气生物学的贡献。

Projections of the effects of climate change on allergic asthma: the contribution of aerobiology.

机构信息

Interdepartmental Centre of Bioclimatology, University of Florence, Florence, Italy.

出版信息

Allergy. 2010 Sep;65(9):1073-81. doi: 10.1111/j.1398-9995.2010.02423.x. Epub 2010 Jun 17.

DOI:10.1111/j.1398-9995.2010.02423.x
PMID:20560904
Abstract

Climate change is unequivocal and represents a possible threat for patients affected by allergic conditions. It has already had an impact on living organisms, including plants and fungi with current scenarios projecting further effects by the end of the century. Over the last three decades, studies have shown changes in production, dispersion and allergen content of pollen and spores, which may be region- and species-specific. In addition, these changes may have been influenced by urban air pollutants interacting directly with pollen. Data suggest an increasing effect of aeroallergens on allergic patients over this period, which may also imply a greater likelihood of the development of an allergic respiratory disease in sensitized subjects and exacerbation of symptomatic patients. There are a number of limitations that make predictions uncertain, and further and specifically designed studies are needed to clarify current effects and future scenarios. We recommend: More stress on pollen/spore exposure in the diagnosis and treatment guidelines of respiratory and allergic diseases; collection of aerobiological data in a structured way at the European level; creation, promotion and support of multidisciplinary research teams in this area; lobbying the European Union and other funders to finance this research.

摘要

气候变化明确无疑,对患有过敏症的患者构成了潜在威胁。它已经对生物产生了影响,包括植物和真菌,目前的预测显示,到本世纪末还会有进一步的影响。在过去的三十年中,研究表明花粉和孢子的产生、传播和过敏原含量发生了变化,这种变化可能具有地域性和物种特异性。此外,这些变化可能受到与花粉直接相互作用的城市空气污染物的影响。数据表明,在此期间,气传过敏原对过敏患者的影响越来越大,这也意味着致敏患者发生过敏性呼吸道疾病的可能性更大,症状患者的病情恶化的可能性也更大。有许多限制因素使得预测不确定,需要进一步和专门设计的研究来阐明当前的影响和未来的情景。我们建议:在呼吸道和过敏性疾病的诊断和治疗指南中更加重视花粉/孢子暴露;在欧洲层面上以结构化的方式收集空气生物学数据;创建、促进和支持该领域的多学科研究团队;游说欧盟和其他资助者为这项研究提供资金。

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