Li X Y, Wu X Y, Fu C, Shen X F, Yang C B, Wu Y H
Department of Aerospace Medicine, Fourth Military Medical University, Xi'an.
Space Med Med Eng (Beijing). 2000 Aug;13(4):235-9.
Objective. The aim of this study was to determine whether psychomotor performance and visual reaction time were affected by acute exposure to mild or moderate hypoxia. Method. Eighteen healthy male volunteers performed finger tapping, simple reaction time (SRT) and 4-choice reaction time (CRT) tests at simulated altitude of 300 m (control), 2800 m, 3600 m and 4400 m for 1 h in a hypobaric chamber. Result. SaO2 decreased from 98% (control) to 90%, 82% and 74% respectively at the various altitudes. All the performance parameters showed no significant change after exposure to 2800 m for 1 h relative to ground level (P>0.05). However the mean reaction time of 4-CRT under 3600 m prolonged and performance decreased as compared with baseline value (P<0.05), and the performance decreased further under 4400 m (P<0.01). No significant difference was found in finger tapping and SRT even under exposure to 4400 m for 1 h. Furthermore, no decrease in correct rate were observed at any altitude (P>0.05). Conclusion. The results from this study demonstrated that there were no measurable impairment of visual reaction time and psychomotor performance under exposure to an altitude of 2800 m for 1 h. However, adverse effects on psychomotor performance were observed under 3600 m and over.
目的。本研究旨在确定急性暴露于轻度或中度缺氧环境是否会影响心理运动表现和视觉反应时间。方法。18名健康男性志愿者在低压舱中于模拟海拔300米（对照）、2800米、3600米和4400米的环境下进行1小时的手指敲击、简单反应时间（SRT）和四选一反应时间（CRT）测试。结果。在不同海拔高度，动脉血氧饱和度（SaO2）分别从98%（对照）降至90%、82%和74%。暴露于2800米环境1小时后，所有表现参数相对于地面水平均无显著变化（P>0.05）。然而，与基线值相比，在3600米环境下4-CRT的平均反应时间延长，表现下降（P<0.05），在4400米环境下表现进一步下降（P<0.01）。即使在暴露于4400米环境1小时的情况下，手指敲击和SRT也未发现显著差异。此外，在任何海拔高度均未观察到正确率下降（P>0.05）。结论。本研究结果表明，暴露于2800米环境1小时不会对视反应时间和心理运动表现产生可测量的损害。然而，在3600米及以上海拔高度观察到了对心理运动表现的不利影响。
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