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高原暴露所致认知功能障碍的机制、预防与治疗

Mechanism, prevention and treatment of cognitive impairment caused by high altitude exposure.

作者信息

Chen Xin, Zhang Jiexin, Lin Yuan, Li Yan, Wang Han, Wang Zhanhao, Liu Huawei, Hu Yonghe, Liu Lei

机构信息

Department of Clinical Laboratory Medicine, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Chengdu, Sichuan, China.

Faculty of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan, Hubei, China.

出版信息

Front Physiol. 2023 Sep 4;14:1191058. doi: 10.3389/fphys.2023.1191058. eCollection 2023.

Abstract

Hypobaric hypoxia (HH) characteristics induce impaired cognitive function, reduced concentration, and memory. In recent years, an increasing number of people have migrated to high-altitude areas for work and study. Headache, sleep disturbance, and cognitive impairment from HH, severely challenges the physical and mental health and affects their quality of life and work efficiency. This review summarizes the manifestations, mechanisms, and preventive and therapeutic methods of HH environment affecting cognitive function and provides theoretical references for exploring and treating high altitude-induced cognitive impairment.

摘要

低压缺氧(HH)的特征会导致认知功能受损、注意力下降和记忆力减退。近年来,越来越多的人迁移到高海拔地区工作和学习。由HH引起的头痛、睡眠障碍和认知障碍,严重挑战着人们的身心健康,影响他们的生活质量和工作效率。这篇综述总结了HH环境影响认知功能的表现、机制以及预防和治疗方法,为探索和治疗高原性认知障碍提供理论参考。

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