Di Capua E, Stasiak A, Koller T, Brahms S, Thomae R, Pohl F M
Institut für Zellbiologie, ETH, Hönggerberg, Zürich, Switzerland.
EMBO J. 1983;2(9):1531-5. doi: 10.1002/j.1460-2075.1983.tb01619.x.
Above a threshold of torsional stress, the c.d. spectrum of covalently closed circular DNA of natural base sequence acquires a Z-like contribution and antibodies raised against Z-DNA are bound. Mapping of the antibody binding sites by electron microscopy reveals sites which correlate with stretches enriched in alternating purine-pyrimidine sequences and GC base pairs.
Zotero 插件
