Montell Craig, Birnbaumer Lutz, Flockerzi Veit
Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Cell. 2002 Mar 8;108(5):595-8. doi: 10.1016/s0092-8674(02)00670-0.
TRP cation channels display an extraordinary assortment of selectivities and activation mechanisms, some of which represent previously unrecognized modes for regulating ion channels. Moreover, the biological roles of TRP channels appear to be equally diverse and range from roles in pain perception to male aggression.
瞬时受体电位(TRP)阳离子通道表现出极其多样的选择性和激活机制,其中一些代表了调节离子通道的前所未有的模式。此外,TRP通道的生物学作用似乎同样多样,涵盖从痛觉感知到雄性攻击行为等多个方面。