转录起始中的共激活因子：这是你的指令。
Coactivators in transcription initiation: here are your orders.
作者信息
Featherstone Mark
机构信息
McGill Cancer Centre, 3655 Promenade Sir William Osler, Montreal, QC H3G 1Y6, Canada.
出版信息
Curr Opin Genet Dev. 2002 Apr;12(2):149-55. doi: 10.1016/s0959-437x(02)00280-0.
Abstract
Coactivators are diverse and multifunctional proteins that act downstream of DNA-binding activators to stimulate transcription. Recent studies elucidate the temporal sequence in which coactivators are recruited to target promoters, and how their enzymatic properties and molecular interactions culminate in transcriptional initiation.
摘要
共激活因子是多种多样且具有多种功能的蛋白质，它们在DNA结合激活因子的下游发挥作用以刺激转录。最近的研究阐明了共激活因子被招募到靶启动子的时间顺序，以及它们的酶活性和分子相互作用如何最终导致转录起始。
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