The CREB family of transcription activators.
作者信息
Brindle P K, Montminy M R
机构信息
Salk Institute for Biological Science, La Jolla, California.
出版信息
Curr Opin Genet Dev. 1992 Apr;2(2):199-204. doi: 10.1016/s0959-437x(05)80274-6.
PMID:1386267
Abstract
A diverse family of transcription factors bind to the cAMP-response elements found in a variety of mammalian and viral gene promoters. One of the members of this family, CREB, is being intensively studied so as to elucidate the mechanisms by which second messenger signal transduction pathways act to positively and negatively regulate transcription.
摘要
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